Anesthetic Management and Surgical Site Infections in Total Hip or Knee Replacement ~A Population-based Study. Anesthesiology. 113(2):279-284, August 2010.
Results: Of the 3,081 sampled patients, 56 patients (1.8%)had 30-day SSIs; 33 (2.8% of all under general anesthesia) of them had general anesthesia, and 23 (1.2% of all under epidural or spinal anesthesia) had epidural or spinal anesthesia (P=0.002). The odds of SSI for patients receiving total hip or knee replacement under general anesthesia were 2.21 (95% CI=1.25–3.90, P=0.007) times higher than those who had the same procedure under epidural or spinal anesthesia, after adjusting for the patient’s age, sex, the year of surgery, comorbidities, surgeon’s age, and hospital teaching status.